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The Transcriptional and Protein Profile From Human Infected Neuroprogenitor Cells Is Strongly Correlated to Zika Virus Microcephaly Cytokines Phenotype Evidencing a Persistent Inflammation in the CNS
Zika virus (ZIKV) infection during pregnancy is associated with microcephaly, a congenital malformation resulting from neuroinflammation and direct effects of virus replication on the developing central nervous system (CNS). However, the exact changes in the affected CNS remain unknown. Here, we sho...
Autores principales: | Lima, Morganna C., de Mendonça, Leila R., Rezende, Antonio M., Carrera, Raquel M., Aníbal-Silva, Conceição E., Demers, Matthew, D'Aiuto, Leonardo, Wood, Joel, Chowdari, Kodavali V., Griffiths, Michael, Lucena-Araujo, Antonio R., Barral-Netto, Manoel, Azevedo, Elisa A. N., Alves, Renan W., Farias, Pablo C. S., Marques, Ernesto T. A., Castanha, Priscila M. S., Donald, Claire L., Kohl, Alain, Nimgaonkar, Vishwajit L., Franca, Rafael F. O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707094/ https://www.ncbi.nlm.nih.gov/pubmed/31474994 http://dx.doi.org/10.3389/fimmu.2019.01928 |
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