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MT2A is an early predictive biomarker of response to chemotherapy and a potential therapeutic target in osteosarcoma

Osteosarcoma is the most prevalent primary bone malignancy in children and young adults. Resistance to chemotherapy remains a key challenge for effective treatment of patients with osteosarcoma. The aim of the present study was to investigate the preventive role of metallothionein-2A (MT2A) in respo...

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Detalles Bibliográficos
Autores principales: Mangelinck, Adèle, da Costa, Maria Eugénia Marques, Stefanovska, Bojana, Bawa, Olivia, Polrot, Mélanie, Gaspar, Nathalie, Fromigué, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707240/
https://www.ncbi.nlm.nih.gov/pubmed/31444479
http://dx.doi.org/10.1038/s41598-019-48846-2