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Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors

The culture of human induced pluripotent stem cells (hiPSCs) at large scale becomes feasible with the aid of scalable suspension setups in continuously stirred tank reactors (CSTRs). Innovative monitoring options and emerging automated process control strategies allow for the necessary highly define...

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Detalles Bibliográficos
Autores principales: Schwedhelm, Ivo, Zdzieblo, Daniela, Appelt-Menzel, Antje, Berger, Constantin, Schmitz, Tobias, Schuldt, Bernhard, Franke, Andre, Müller, Franz-Josef, Pless, Ole, Schwarz, Thomas, Wiedemann, Philipp, Walles, Heike, Hansmann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707254/
https://www.ncbi.nlm.nih.gov/pubmed/31444389
http://dx.doi.org/10.1038/s41598-019-48814-w