Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening

Pioneer transcription factors are characterized by having the unique property of enabling the opening of closed chromatin sites, for implementation of cell fates. We previously found that the pioneer Pax7 specifies melanotrope cells through deployment of an enhancer repertoire, which allows binding...

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Detalles Bibliográficos
Autores principales: Mayran, Alexandre, Sochodolsky, Kevin, Khetchoumian, Konstantin, Harris, Juliette, Gauthier, Yves, Bemmo, Amandine, Balsalobre, Aurelio, Drouin, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707328/
https://www.ncbi.nlm.nih.gov/pubmed/31444346
http://dx.doi.org/10.1038/s41467-019-11791-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707328/
https://www.ncbi.nlm.nih.gov/pubmed/31444346
http://dx.doi.org/10.1038/s41467-019-11791-9

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