Cargando…
Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
Pioneer transcription factors are characterized by having the unique property of enabling the opening of closed chromatin sites, for implementation of cell fates. We previously found that the pioneer Pax7 specifies melanotrope cells through deployment of an enhancer repertoire, which allows binding...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707328/ https://www.ncbi.nlm.nih.gov/pubmed/31444346 http://dx.doi.org/10.1038/s41467-019-11791-9 |