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Bone marrow mesenchymal stem cell-derived exosomes attenuate D-GaIN/LPS-induced hepatocyte apoptosis by activating autophagy in vitro

BACKGROUND: Acute liver failure is an inflammation-mediated hepatocyte injury. Mesenchymal stem cell (MSC) transplantation is currently considered to be an effective treatment strategy for acute liver failure. Exosomes are an important paracrine factor that can be used as a direct therapeutic agent....

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Detalles Bibliográficos
Autores principales: Zhao, Shuxian, Liu, Yan, Pu, Zenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707369/
https://www.ncbi.nlm.nih.gov/pubmed/31695322
http://dx.doi.org/10.2147/DDDT.S220190