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Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)

BACKGROUND: Visceral leishmaniasis is a complex neglected tropical disease caused by Leishmania donovani complex. Its current treatment reveals strong limitations, especially high toxicity. In this context, natural products are important sources of new drug alternatives for VL therapy. Therefore, th...

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Detalles Bibliográficos
Autores principales: da Costa-Silva, Thais A., Conserva, Geanne A. Alves, Galisteo, Andrés J., Tempone, Andre G., Lago, João Henrique G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707387/
https://www.ncbi.nlm.nih.gov/pubmed/31467511
http://dx.doi.org/10.1590/1678-9199-JVATITD-2019-0008