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Classification of the nucleolytic ribozymes based upon catalytic mechanism
The nucleolytic ribozymes carry out site-specific RNA cleavage reactions by nucleophilic attack of the 2′-oxygen atom on the adjacent phosphorus with an acceleration of a million-fold or greater. A major part of this arises from concerted general acid–base catalysis. Recent identification of new rib...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707401/ https://www.ncbi.nlm.nih.gov/pubmed/31489181 http://dx.doi.org/10.12688/f1000research.19324.1 |