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RNases Disrupt the Adaptive Potential of Malignant Cells: Perspectives for Therapy

Exogenous RNases are selectively toxic to tumor cells. The reasons for this selectivity are not quite clear and should be searched for in the properties that distinguish malignant from normal cells. During onco-transformation, cells acquire properties allowing them to adapt to the altered microenvir...

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Detalles Bibliográficos
Autores principales: Mitkevich, Vladimir Alexandrovich, Petrushanko, Irina Yu, Makarov, Alexander Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707412/
https://www.ncbi.nlm.nih.gov/pubmed/31474868
http://dx.doi.org/10.3389/fphar.2019.00922