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Mitochondrial Network State Scales mtDNA Genetic Dynamics

Mitochondrial DNA (mtDNA) mutations cause severe congenital diseases but may also be associated with healthy aging. mtDNA is stochastically replicated and degraded, and exists within organelles which undergo dynamic fusion and fission. The role of the resulting mitochondrial networks in the time evo...

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Detalles Bibliográficos
Autores principales: Aryaman, Juvid, Bowles, Charlotte, Jones, Nick S., Johnston, Iain G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707450/
https://www.ncbi.nlm.nih.gov/pubmed/31253641
http://dx.doi.org/10.1534/genetics.119.302423