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A Novel Gene Underlies Bleomycin-Response Variation in Caenorhabditis elegans

Bleomycin is a powerful chemotherapeutic drug used to treat a variety of cancers. However, individual patients vary in their responses to bleomycin. The identification of genetic differences that underlie this response variation could improve treatment outcomes by tailoring bleomycin dosages to each...

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Detalles Bibliográficos
Autores principales: Brady, Shannon C., Zdraljevic, Stefan, Bisaga, Karol W., Tanny, Robyn E., Cook, Daniel E., Lee, Daehan, Wang, Ye, Andersen, Erik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707474/
https://www.ncbi.nlm.nih.gov/pubmed/31171655
http://dx.doi.org/10.1534/genetics.119.302286