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Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies

BACKGROUND: Severe falciparum malaria is a medical emergency characterised by potentially lethal vital organ dysfunction. Patient fatality rates even with parenteral artesunate treatment remain high. Despite considerable research into adjuvant therapies targeting organ and tissue dysfunction, none h...

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Detalles Bibliográficos
Autores principales: Leopold, Stije J., Watson, James A., Jeeyapant, Atthanee, Simpson, Julie A., Phu, Nguyen H., Hien, Tran T., Day, Nicholas P. J., Dondorp, Arjen M., White, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707545/
https://www.ncbi.nlm.nih.gov/pubmed/31442221
http://dx.doi.org/10.1371/journal.pmed.1002858