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Mouse models of hereditary hemochromatosis do not develop early liver fibrosis in response to a high fat diet

Hepatic iron overload, a hallmark of hereditary hemochromatosis, triggers progressive liver disease. There is also increasing evidence for a pathogenic role of iron in non-alcoholic fatty liver disease (NAFLD), which may progress to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis and hepat...

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Detalles Bibliográficos
Autores principales: Wagner, John, Fillebeen, Carine, Haliotis, Tina, Charlebois, Edouard, Katsarou, Angeliki, Mui, Jeannie, Vali, Hojatollah, Pantopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707558/
https://www.ncbi.nlm.nih.gov/pubmed/31442254
http://dx.doi.org/10.1371/journal.pone.0221455