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H3K4 dimethylation at FosB promoter in the striatum of chronic stressed rats promotes morphine-induced conditioned place preference

Expression of FosB gene in striatum is essential in addiction establishment. Activated glucocorticoid receptors (GRs) induce FosB gene expression in response to stressor. Therefore, elevation of FosB expression in striatum serves as one mechanism by which stress increases risk for addiction. In this...

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Detalles Bibliográficos
Autores principales: Chen, Minghui, Zhang, Xiaojie, Hao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707596/
https://www.ncbi.nlm.nih.gov/pubmed/31442272
http://dx.doi.org/10.1371/journal.pone.0221506