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DNA methyltransferase inhibitor suppresses fibrogenetic changes in human conjunctival fibroblasts

PURPOSE: This study aimed to clarify the effects of a DNA methyltransferase inhibitor on fibrogenetic changes in human conjunctival fibroblasts (HConF). METHODS: HConF were pretreated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine (5-Aza-dC) for 48 h. After one passage, the cel...

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Detalles Bibliográficos
Autores principales: Yonemura, Hitomi, Futakuchi, Akiko, Inoue-Mochita, Miyuki, Fujimoto, Tomokazu, Takahashi, Eri, Tanihara, Hidenobu, Inoue, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707755/
https://www.ncbi.nlm.nih.gov/pubmed/31523116