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Safety Considerations in the Development of Hippo Pathway Inhibitors in Cancers

The Hippo pathway is a critical regulator of cell and organ growth and has emerged as a target for therapeutic intervention in cancers. Its signaling is thought to play an important role in various physiological processes including homeostasis and tissue regeneration. To date there has been limited...

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Detalles Bibliográficos
Autores principales: Kakiuchi-Kiyota, Satoko, Schutten, Melissa M., Zhong, Yu, Crawford, James J., Dey, Anwesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707765/
https://www.ncbi.nlm.nih.gov/pubmed/31475147
http://dx.doi.org/10.3389/fcell.2019.00156