Cargando…
Safety Considerations in the Development of Hippo Pathway Inhibitors in Cancers
The Hippo pathway is a critical regulator of cell and organ growth and has emerged as a target for therapeutic intervention in cancers. Its signaling is thought to play an important role in various physiological processes including homeostasis and tissue regeneration. To date there has been limited...
Autores principales: | Kakiuchi-Kiyota, Satoko, Schutten, Melissa M., Zhong, Yu, Crawford, James J., Dey, Anwesha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707765/ https://www.ncbi.nlm.nih.gov/pubmed/31475147 http://dx.doi.org/10.3389/fcell.2019.00156 |
Ejemplares similares
-
Hippo Signaling Pathway in Pancreas Development
por: Wu, Yifan, et al.
Publicado: (2021) -
The Hippo Signaling Pathway in Cardiac Development and Diseases
por: Mia, Masum M., et al.
Publicado: (2019) -
Mob Family Proteins: Regulatory Partners in Hippo and Hippo-Like Intracellular Signaling Pathways
por: Duhart, Juan Carlos, et al.
Publicado: (2020) -
Strong as a Hippo’s Heart: Biomechanical Hippo Signaling During Zebrafish Cardiac Development
por: Bornhorst, Dorothee, et al.
Publicado: (2021) -
Role of Hippo Pathway-YAP/TAZ Signaling in Angiogenesis
por: Boopathy, Gandhi T. K., et al.
Publicado: (2019)