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Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry

Multiple sclerosis (MS) is characterized by demyelinated and inflammatory lesions in the brain and spinal cord that are highly variable in terms of cellular content. Here, we used imaging mass cytometry (IMC) to enable the simultaneous imaging of 15+ proteins within staged MS lesions. To test the po...

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Detalles Bibliográficos
Autores principales: Ramaglia, Valeria, Sheikh-Mohamed, Salma, Legg, Karen, Park, Calvin, Rojas, Olga L, Zandee, Stephanie, Fu, Fred, Ornatsky, Olga, Swanson, Eric C, Pitt, David, Prat, Alexandre, McKee, Trevor D, Gommerman, Jennifer L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707785/
https://www.ncbi.nlm.nih.gov/pubmed/31368890
http://dx.doi.org/10.7554/eLife.48051