Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses

Macrophages are activated during microbial infection to coordinate inflammatory responses and host defense. Here we found that in macrophages activated by bacterial lipopolysaccharide (LPS), mitochondrial glycerol 3-phosphate dehydrogenase (GPD2) regulated glucose oxidation to drive inflammatory res...

Descripción completa

Detalles Bibliográficos
Autores principales: Langston, P. Kent, Nambu, Aya, Jung, Jonathan, Shibata, Munehiko, Aksoylar, H. Ibrahim, Lei, Jiahui, Xu, Peining, Doan, Mary T., Jiang, Helen, MacArthur, Michael R., Gao, Xia, Kong, Yong, Chouchani, Edward T., Locasale, Jason W., Synder, Nathaniel W., Horng, Tiffany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707851/
https://www.ncbi.nlm.nih.gov/pubmed/31384058
http://dx.doi.org/10.1038/s41590-019-0453-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707851/
https://www.ncbi.nlm.nih.gov/pubmed/31384058
http://dx.doi.org/10.1038/s41590-019-0453-7

Ejemplares similares