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The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage

Innate lymphoid cells (ILCs) play important functions in immunity and tissue homeostasis, but their development is poorly understood. Through the use of single-cell approaches, we examined the transcriptional and functional heterogeneity of ILC progenitors and studied the precursor–product relations...

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Detalles Bibliográficos
Autores principales: Harly, Christelle, Kenney, Devin, Ren, Gang, Lai, Binbin, Raabe, Tobias, Yang, Qi, Cam, Margaret C., Xue, Hai-Hui, Zhao, Keji, Bhandoola, Avinash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707869/
https://www.ncbi.nlm.nih.gov/pubmed/31358996
http://dx.doi.org/10.1038/s41590-019-0445-7