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An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development

Classical type 1 dendritic cells (cDC1s) are required for anti-viral and anti-tumor immunity, which necessitates an understanding of their development. Development of the cDC1 progenitor requires an E protein–dependent enhancer located 41 kilobases downstream of the transcription start site of the t...

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Detalles Bibliográficos
Autores principales: Bagadia, Prachi, Huang, Xiao, Liu, Tiantian, Durai, Vivek, Grajales-Reyes, Gary E., Nitschke, Maximilian, Modrusan, Zora, Granja, Jeffrey M., Satpathy, Ansuman T., Briseño, Carlos G., Gargaro, Marco, Iwata, Arifumi, Kim, Sunkyung, Chang, Howard Y., Shaw, Andrey S., Murphy, Theresa L., Murphy, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707889/
https://www.ncbi.nlm.nih.gov/pubmed/31406377
http://dx.doi.org/10.1038/s41590-019-0449-3