Cargando…
An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development
Classical type 1 dendritic cells (cDC1s) are required for anti-viral and anti-tumor immunity, which necessitates an understanding of their development. Development of the cDC1 progenitor requires an E protein–dependent enhancer located 41 kilobases downstream of the transcription start site of the t...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707889/ https://www.ncbi.nlm.nih.gov/pubmed/31406377 http://dx.doi.org/10.1038/s41590-019-0449-3 |