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An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development
Classical type 1 dendritic cells (cDC1s) are required for anti-viral and anti-tumor immunity, which necessitates an understanding of their development. Development of the cDC1 progenitor requires an E protein–dependent enhancer located 41 kilobases downstream of the transcription start site of the t...
Autores principales: | Bagadia, Prachi, Huang, Xiao, Liu, Tiantian, Durai, Vivek, Grajales-Reyes, Gary E., Nitschke, Maximilian, Modrusan, Zora, Granja, Jeffrey M., Satpathy, Ansuman T., Briseño, Carlos G., Gargaro, Marco, Iwata, Arifumi, Kim, Sunkyung, Chang, Howard Y., Shaw, Andrey S., Murphy, Theresa L., Murphy, Kenneth M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707889/ https://www.ncbi.nlm.nih.gov/pubmed/31406377 http://dx.doi.org/10.1038/s41590-019-0449-3 |
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