SERCA2a tyrosine nitration coincides with impairments in maximal SERCA activity in left ventricles from tafazzin‐deficient mice

The sarco/endoplasmic reticulum Ca(2+)‐ATPase (SERCA) is imperative for normal cardiac function regulating both muscle relaxation and contractility. SERCA2a is the predominant isoform in cardiac muscles and is inhibited by phospholamban (PLN). Under conditions of oxidative stress, SERCA2a may also b...

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Detalles Bibliográficos
Autores principales: Braun, Jessica L., Hamstra, Sophie I., Messner, Holt N., Fajardo, Val A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708055/
https://www.ncbi.nlm.nih.gov/pubmed/31444868
http://dx.doi.org/10.14814/phy2.14215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708055/
https://www.ncbi.nlm.nih.gov/pubmed/31444868
http://dx.doi.org/10.14814/phy2.14215

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