Upregulation of CKIP-1 inhibits high-glucose induced inflammation and oxidative stress in HRECs and attenuates diabetic retinopathy by modulating Nrf2/ARE signaling pathway: an in vitro study

PURPOSE: The aim of this study was to investigate the underlying mechanisms of diabetic retinopathy (DR) development. METHODS: Real-Time qPCR was used to detect Casein kinase 2 interacting protein-1 (CKIP-1) and Nuclear factor E2-related factor 2 (Nrf2) mRNA levels. Western Blot was employed to dete...

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Detalles Bibliográficos
Autores principales: Zhang, Lan, Yu, Jie, Ye, Mingxia, Zhao, Hailan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708125/
https://www.ncbi.nlm.nih.gov/pubmed/31462987
http://dx.doi.org/10.1186/s13578-019-0331-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708125/
https://www.ncbi.nlm.nih.gov/pubmed/31462987
http://dx.doi.org/10.1186/s13578-019-0331-x

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