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Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and human papillomavirus (HPV) has been increasingly recognized as a pathogenic factor for the initiation and development of HNSCC. E6 oncogene, an essential component of the HPV 16 virus, acts as a l...

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Detalles Bibliográficos
Autores principales: Jin, Yu, Li, Yuexiu, Wang, Xin, Yang, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708138/
https://www.ncbi.nlm.nih.gov/pubmed/31462893
http://dx.doi.org/10.1186/s12935-019-0942-7