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A new primer construction technique that effectively increases amplification of rare mutant templates in samples

BACKGROUND: In personalized medicine, companion diagnostic tests provide additional information to help select a treatment option likely to be optimal for a patient. Although such tests include several techniques for detecting low levels of mutant genes in wild-type backgrounds with fairly high sens...

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Detalles Bibliográficos
Autores principales: Huang, Jr-Kai, Fan, Ling, Wang, Tao-Yeuan, Wu, Pao-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708177/
https://www.ncbi.nlm.nih.gov/pubmed/31443709
http://dx.doi.org/10.1186/s12896-019-0555-1