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A new primer construction technique that effectively increases amplification of rare mutant templates in samples
BACKGROUND: In personalized medicine, companion diagnostic tests provide additional information to help select a treatment option likely to be optimal for a patient. Although such tests include several techniques for detecting low levels of mutant genes in wild-type backgrounds with fairly high sens...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708177/ https://www.ncbi.nlm.nih.gov/pubmed/31443709 http://dx.doi.org/10.1186/s12896-019-0555-1 |