Restore natural fertility of Kit(w)/Kit(wv) mouse with nonobstructive azoospermia through gene editing on SSCs mediated by CRISPR-Cas9

BACKGROUND: Male infertility is a serious social problem in modern society. Nonobstructive azoospermia (NOA) caused by germ cell gene defects is an important reason for male infertility, but effective clinical treatment for this disease has not been established. METHODS: We choose Kit(w)/Kit(wv) mou...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyu, Sun, Tiecheng, Wang, Xiuxia, Tang, Jixin, Liu, Yixun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708192/
https://www.ncbi.nlm.nih.gov/pubmed/31445521
http://dx.doi.org/10.1186/s13287-019-1386-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708192/
https://www.ncbi.nlm.nih.gov/pubmed/31445521
http://dx.doi.org/10.1186/s13287-019-1386-7

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