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Umbrella and basket trials in oncology: ethical challenges

BACKGROUND: Novel precision oncology trial designs, such as basket and umbrella trials, are designed to test new anticancer agents in more effective and affordable ways. However, they present some ethical concerns referred to scientific validity, risk-benefit balance and informed consent. Our aim is...

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Detalles Bibliográficos
Autores principales: Strzebonska, Karolina, Waligora, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708208/
https://www.ncbi.nlm.nih.gov/pubmed/31443704
http://dx.doi.org/10.1186/s12910-019-0395-5