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Target-small decoy search strategy for false discovery rate estimation

BACKGROUND: One of the most important steps in peptide identification is to estimate the false discovery rate (FDR). The most commonly used method for estimating FDR is the target-decoy search strategy (TDS). While this method is simple and effective, it is time/space-inefficient because it searches...

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Detalles Bibliográficos
Autores principales: Kim, Hyunwoo, Lee, Sangjeong, Park, Heejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708216/
https://www.ncbi.nlm.nih.gov/pubmed/31443634
http://dx.doi.org/10.1186/s12859-019-3034-8