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YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT

BACKGROUND: Myocardial fibrosis is a common pathophysiological change in cardiovascular disease, which can cause cardiac dysfunction and even sudden death. Excessively activated fibroblasts proliferate and secret excessive extracellular matrix (ECM) components, resulting in normal cardiac structural...

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Detalles Bibliográficos
Autores principales: Lin, Fengxia, Zeng, Zhicong, Song, Yinzhi, Li, Liang, Wu, Zijun, Zhang, Xiaoduo, Li, Zhiwen, Ke, Xiao, Hu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708233/
https://www.ncbi.nlm.nih.gov/pubmed/31443679
http://dx.doi.org/10.1186/s13287-019-1377-8