Cargando…

LncRNA AFAP1-AS1 promotes tumorigenesis and epithelial-mesenchymal transition of osteosarcoma through RhoC/ROCK1/p38MAPK/Twist1 signaling pathway

BACKGROUND: An increasing number of studies have demonstrated that long non-coding RNAs (lncRNAs) play pivotal roles in cancer onset and development. LncRNA AFAP1-AS1 has been validated to be abnormally upregulated and play oncogenic roles in various malignant tumors. The biological role and mechani...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Deyao, Wu, Fashuai, Mu, Shidai, Hu, Binwu, Zhong, Binlong, Gao, Feng, Qing, Xiangcheng, Liu, Jianxiang, Zhang, Zhicai, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708246/
https://www.ncbi.nlm.nih.gov/pubmed/31443665
http://dx.doi.org/10.1186/s13046-019-1363-0