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LncRNA AFAP1-AS1 promotes tumorigenesis and epithelial-mesenchymal transition of osteosarcoma through RhoC/ROCK1/p38MAPK/Twist1 signaling pathway

BACKGROUND: An increasing number of studies have demonstrated that long non-coding RNAs (lncRNAs) play pivotal roles in cancer onset and development. LncRNA AFAP1-AS1 has been validated to be abnormally upregulated and play oncogenic roles in various malignant tumors. The biological role and mechani...

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Detalles Bibliográficos
Autores principales:	Shi, Deyao, Wu, Fashuai, Mu, Shidai, Hu, Binwu, Zhong, Binlong, Gao, Feng, Qing, Xiangcheng, Liu, Jianxiang, Zhang, Zhicai, Shao, Zengwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708246/ https://www.ncbi.nlm.nih.gov/pubmed/31443665 http://dx.doi.org/10.1186/s13046-019-1363-0

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