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Neoantigen vaccine: an emerging tumor immunotherapy

Genetic instability of tumor cells often leads to the occurrence of a large number of mutations, and expression of non-synonymous mutations can produce tumor-specific antigens called neoantigens. Neoantigens are highly immunogenic as they are not expressed in normal tissues. They can activate CD4+ a...

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Detalles Bibliográficos
Autores principales: Peng, Miao, Mo, Yongzhen, Wang, Yian, Wu, Pan, Zhang, Yijie, Xiong, Fang, Guo, Can, Wu, Xu, Li, Yong, Li, Xiaoling, Li, Guiyuan, Xiong, Wei, Zeng, Zhaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708248/
https://www.ncbi.nlm.nih.gov/pubmed/31443694
http://dx.doi.org/10.1186/s12943-019-1055-6