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Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity

BACKGROUND: The pathology of chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and most lung cancers involves the small airway epithelium (SAE), the single continuous layer of cells lining the airways ≥ 6th generations. The basal cells (BC) are the stem/progenitor cel...

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Detalles Bibliográficos
Autores principales: Wang, Guoqing, Lou, Howard H., Salit, Jacqueline, Leopold, Philip L., Driscoll, Sharon, Schymeinsky, Juergen, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S., Thomas, Matthew J., Crystal, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708250/
https://www.ncbi.nlm.nih.gov/pubmed/31443657
http://dx.doi.org/10.1186/s12931-019-1140-9