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BCL6 regulates brown adipocyte dormancy to maintain thermogenic reserve and fitness

Brown adipocytes provide a metabolic defense against environmental cold but become dormant as mammals habituate to warm environments. Although dormancy is a regulated response in brown adipocytes to environmental warmth, its transcriptional mechanisms and functional importance are unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Kutyavin, Vassily I., Chawla, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708354/
https://www.ncbi.nlm.nih.gov/pubmed/31375635
http://dx.doi.org/10.1073/pnas.1907308116