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Comprehensive assessment of HER2 alteration in a colorectal cancer cohort: from next-generation sequencing to clinical significance

PURPOSE: Human epidermal growth factor receptor 2 (HER2) is an emerging therapeutic target in colorectal cancer (CRC). Currently, immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) have been used to determine HER2-positive CRCs; however, the clinical utility of next-generation...

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Detalles Bibliográficos
Autores principales: Yeh, Yu-Min, Lee, Chun-Hui, Chen, Shang-Hung, Lee, Chung-Ta, Chen, Yi-Lin, Lin, Bo-Wen, Lin, Shao-Chieh, Chan, Ren-Hao, Lee, Jenq-Chang, Shen, Meng-Ru, Lin, Peng-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708395/
https://www.ncbi.nlm.nih.gov/pubmed/31692488
http://dx.doi.org/10.2147/CMAR.S213247