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Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis

PURPOSE: The tripartite motif (TRIM)16 acts as a tumour suppressor in both squamous cell carcinoma (SCC) and melanoma. TRIM16 is known to be secreted by keratinocytes, but no studies have been reported yet to assess the relationship between TRIM16 keratinocyte expression and melanoma development. ME...

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Detalles Bibliográficos
Autores principales: Sutton, Selina K., Cheung, Belamy B., Massudi, Hassina, Tan, Owen, Koach, Jessica, Mayoh, Chelsea, Carter, Daniel R., Marshall, Glenn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708510/
https://www.ncbi.nlm.nih.gov/pubmed/31342168
http://dx.doi.org/10.1007/s00432-019-02981-5