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Loss of enhancer of zeste homologue 2 (EZH2) at tumor invasion front is correlated with higher aggressiveness in colorectal cancer cells

PURPOSE: Enhancer of zeste homolog 2 (EZH2) is associated with epigenetic gene silencing and aggressiveness in many tumor types. However, the prognostic impact of high EZH2 expression is controversially discussed for colorectal cancer. For this reason, we immunohistochemically analyzed EZH2 expressi...

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Detalles Bibliográficos
Autores principales: Böhm, Julian, Muenzner, Julienne Kathrin, Caliskan, Aylin, Ndreshkjana, Benardina, Erlenbach-Wünsch, Katharina, Merkel, Susanne, Croner, Roland, Rau, Tilman T., Geppert, Carol Immanuel, Hartmann, Arndt, Roehe, Adriana Vial, Schneider-Stock, Regine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708512/
https://www.ncbi.nlm.nih.gov/pubmed/31317325
http://dx.doi.org/10.1007/s00432-019-02977-1