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Loss of enhancer of zeste homologue 2 (EZH2) at tumor invasion front is correlated with higher aggressiveness in colorectal cancer cells
PURPOSE: Enhancer of zeste homolog 2 (EZH2) is associated with epigenetic gene silencing and aggressiveness in many tumor types. However, the prognostic impact of high EZH2 expression is controversially discussed for colorectal cancer. For this reason, we immunohistochemically analyzed EZH2 expressi...
Autores principales: | Böhm, Julian, Muenzner, Julienne Kathrin, Caliskan, Aylin, Ndreshkjana, Benardina, Erlenbach-Wünsch, Katharina, Merkel, Susanne, Croner, Roland, Rau, Tilman T., Geppert, Carol Immanuel, Hartmann, Arndt, Roehe, Adriana Vial, Schneider-Stock, Regine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708512/ https://www.ncbi.nlm.nih.gov/pubmed/31317325 http://dx.doi.org/10.1007/s00432-019-02977-1 |
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