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Acute myeloid leukemia with adult atopic dermatitis as first manifestation: A case report
RATIONALE: Atopic dermatitis (AD) is a chronic recurrent dermatitis with profound itching, which could be the first manifestation of acute myeloid leukemia (AML). PATIENT CONCERNS: A 53-year-old Chinese man suffered a 6-month history of systemic symmetrical dermatitis, accompanied with profound itch...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708621/ https://www.ncbi.nlm.nih.gov/pubmed/31393345 http://dx.doi.org/10.1097/MD.0000000000016362 |
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author | Ma, Wei-Wei Kasyanju Carrero, Lorna Martin Yin, Xu-Feng Liu, Hou-Fang Zhou, Bing-Rong |
author_facet | Ma, Wei-Wei Kasyanju Carrero, Lorna Martin Yin, Xu-Feng Liu, Hou-Fang Zhou, Bing-Rong |
author_sort | Ma, Wei-Wei |
collection | PubMed |
description | RATIONALE: Atopic dermatitis (AD) is a chronic recurrent dermatitis with profound itching, which could be the first manifestation of acute myeloid leukemia (AML). PATIENT CONCERNS: A 53-year-old Chinese man suffered a 6-month history of systemic symmetrical dermatitis, accompanied with profound itching. The patient was diagnosed as “eczema” in several hospitals, and the effects of antihistamine and topical steroid creams were poor. Nocturnal sleep was seriously affected by aggravating pruritus. Laboratorial examination was compatible with AML-M4. DIAGNOSES: AML-M4 with AD as first manifestation. INTERVENTIONS: IA regimen (ayninen and cytarabine) were used in induction chemotherapy. However, the patient did not achieve complete remission, and although his rash had improved, he still experienced severely general body itching. On the seventh day of chemotherapy, the patient entered the period of granulocyte deficiency with infection. OUTCOMES: The patient died due to septic shock after chemotherapy. LESSONS: The case strengthens the awareness of AML with AD as first manifestation and raises oncological vigilance in patients with AD refractory. |
format | Online Article Text |
id | pubmed-6708621 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-67086212019-10-01 Acute myeloid leukemia with adult atopic dermatitis as first manifestation: A case report Ma, Wei-Wei Kasyanju Carrero, Lorna Martin Yin, Xu-Feng Liu, Hou-Fang Zhou, Bing-Rong Medicine (Baltimore) Research Article RATIONALE: Atopic dermatitis (AD) is a chronic recurrent dermatitis with profound itching, which could be the first manifestation of acute myeloid leukemia (AML). PATIENT CONCERNS: A 53-year-old Chinese man suffered a 6-month history of systemic symmetrical dermatitis, accompanied with profound itching. The patient was diagnosed as “eczema” in several hospitals, and the effects of antihistamine and topical steroid creams were poor. Nocturnal sleep was seriously affected by aggravating pruritus. Laboratorial examination was compatible with AML-M4. DIAGNOSES: AML-M4 with AD as first manifestation. INTERVENTIONS: IA regimen (ayninen and cytarabine) were used in induction chemotherapy. However, the patient did not achieve complete remission, and although his rash had improved, he still experienced severely general body itching. On the seventh day of chemotherapy, the patient entered the period of granulocyte deficiency with infection. OUTCOMES: The patient died due to septic shock after chemotherapy. LESSONS: The case strengthens the awareness of AML with AD as first manifestation and raises oncological vigilance in patients with AD refractory. Wolters Kluwer Health 2019-08-09 /pmc/articles/PMC6708621/ /pubmed/31393345 http://dx.doi.org/10.1097/MD.0000000000016362 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | Research Article Ma, Wei-Wei Kasyanju Carrero, Lorna Martin Yin, Xu-Feng Liu, Hou-Fang Zhou, Bing-Rong Acute myeloid leukemia with adult atopic dermatitis as first manifestation: A case report |
title | Acute myeloid leukemia with adult atopic dermatitis as first manifestation: A case report |
title_full | Acute myeloid leukemia with adult atopic dermatitis as first manifestation: A case report |
title_fullStr | Acute myeloid leukemia with adult atopic dermatitis as first manifestation: A case report |
title_full_unstemmed | Acute myeloid leukemia with adult atopic dermatitis as first manifestation: A case report |
title_short | Acute myeloid leukemia with adult atopic dermatitis as first manifestation: A case report |
title_sort | acute myeloid leukemia with adult atopic dermatitis as first manifestation: a case report |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708621/ https://www.ncbi.nlm.nih.gov/pubmed/31393345 http://dx.doi.org/10.1097/MD.0000000000016362 |
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