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Serum metabolome and targeted bile acid profiling reveals potential novel biomarkers for drug-induced liver injury

This study aims to determine the non-invasive, reliable and sensitive biochemical parameters for the diagnosis of drug-induced liver injury (DILI). Ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) and selected reaction monitoring (SRM) were used to profile the seru...

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Detalles Bibliográficos
Autores principales: Ma, Zhenhua, Wang, Xiaomei, Yin, Peiyuan, Wu, Ruihong, Zhou, Lina, Xu, Guowang, Niu, Junqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708818/
https://www.ncbi.nlm.nih.gov/pubmed/31374067
http://dx.doi.org/10.1097/MD.0000000000016717