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CD4(+)CD25(+)Foxp3(+) regulatory T cells suppress NKG2D-mediated NK cell cytotoxicity in peripheral blood
BACKGROUND: Studies have shown that CD4(+)CD25(+)Foxp3(+)Treg cells suppress NKG2D expression on NK cells via a cell contact-dependent mechanism and increased TGF-β and IL-10 production in some cancer models. We herein aimed to explore whether CD4(+)CD25(+)Foxp3(+)Tregs suppress NKG2D-mediated NK ce...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708973/ https://www.ncbi.nlm.nih.gov/pubmed/31145286 http://dx.doi.org/10.1097/MD.0000000000015722 |