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Connexin 43 Functions as a Positive Regulator of Stem Cell Differentiation into Definitive Endoderm and Pancreatic Progenitors

Efficient stem cell differentiation into pancreatic islet cells is of critical importance for the development of cell replacement therapies for diabetes. Here, we identify the expression pattern of connexin 43 (Cx43), a gap junction (GJ) channel protein, in human embryonic stem cell (hESC)-derived d...

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Detalles Bibliográficos
Autores principales: Yang, Wendy, Lampe, Paul D., Kensel-Hammes, Patricia, Hesson, Jennifer, Ware, Carol B., Crisa, Laura, Cirulli, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708988/
https://www.ncbi.nlm.nih.gov/pubmed/31430690
http://dx.doi.org/10.1016/j.isci.2019.07.033