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Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis

Here, we found two genomic safe harbor (GSH) candidates from chromosomes 3 and 8, based on large-scale population-based cohort data from 4,694 Koreans by CNV analysis. Furthermore, estimated genotype of these CNVRs was validated by quantitative real-time PCR, and epidemiological data examined no sig...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Seo, Moon, Sanghoon, Abu-Bonsrah, Kwaku Dad, Kim, Yun Kyoung, Hwang, Mi Yeong, Kim, Young Jin, Kim, Seokjoong, Hwang, Nathaniel S., Kim, Hyongbum Henry, Kim, Bong-Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708990/
https://www.ncbi.nlm.nih.gov/pubmed/31463366
http://dx.doi.org/10.1016/j.omto.2019.07.001