GPR88 in D1R-Type and D2R-Type Medium Spiny Neurons Differentially Regulates Affective and Motor Behavior

The orphan receptor GPR88 is highly expressed in D1 receptor (D1R)- and D2R-medium spiny neurons (MSNs) and has been associated to striatum-dependent functions in rodents. The total deletion of Gpr88 in mice was shown to decrease anxiety-like behaviors, increase stereotypies and locomotion, and impa...

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Detalles Bibliográficos
Autores principales: Meirsman, A. C., Ben Hamida, Sami, Clarke, E., de Kerchove d’Exaerde, A., Darcq, E., Kieffer, B. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709217/
https://www.ncbi.nlm.nih.gov/pubmed/31346000
http://dx.doi.org/10.1523/ENEURO.0035-19.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709217/
https://www.ncbi.nlm.nih.gov/pubmed/31346000
http://dx.doi.org/10.1523/ENEURO.0035-19.2019

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