Exosomal DNA Aptamer Targeting α-Synuclein Aggregates Reduced Neuropathological Deficits in a Mouse Parkinson’s Disease Model

The α-synuclein aggregates are the main component of Lewy bodies in Parkinson’s disease (PD) brain, and they showed immunotherapy could be employed to alleviate α-synuclein aggregate pathology in PD. Recently we have generated DNA aptamers that specifically recognize α-synuclein. In this study, we f...

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Detalles Bibliográficos
Autores principales: Ren, Xiaoxi, Zhao, Yun, Xue, Fenqin, Zheng, Yan, Huang, Haixia, Wang, Wei, Chang, Yongchang, Yang, Hui, Zhang, Jianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709346/
https://www.ncbi.nlm.nih.gov/pubmed/31437653
http://dx.doi.org/10.1016/j.omtn.2019.07.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709346/
https://www.ncbi.nlm.nih.gov/pubmed/31437653
http://dx.doi.org/10.1016/j.omtn.2019.07.008

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