ZPR1-Dependent Neurodegeneration Is Mediated by the JNK Signaling Pathway

The zinc finger protein ZPR1 deficiency causes neurodegeneration and results in a mild spinal muscular atrophy (SMA)-like disease in mice with reduced Zpr1 gene dosage. Mutation of the survival motor neuron 1 (SMN1) gene causes SMA. Spinal muscular atrophy is characterized by the degeneration of the...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaoting, Kannan, Annapoorna, Gangwani, Laxman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709431/
https://www.ncbi.nlm.nih.gov/pubmed/31488953
http://dx.doi.org/10.1177/1179069519867915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709431/
https://www.ncbi.nlm.nih.gov/pubmed/31488953
http://dx.doi.org/10.1177/1179069519867915

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