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Acquisition of Cross-Resistance to Bedaquiline and Clofazimine following Treatment for Tuberculosis in Pakistan

We report on the first six cases of acquired resistance to bedaquiline in Pakistan. Seventy sequential isolates from 30 drug-resistant-tuberculosis patients on bedaquiline-containing regimens were retrospectively tested for bedaquiline resistance by MIC testing and by the detection of mutations in r...

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Detalles Bibliográficos
Autores principales: Ghodousi, Arash, Rizvi, Alamdar Hussain, Baloch, Aurangzaib Quadir, Ghafoor, Abdul, Khanzada, Faisal Masood, Qadir, Mehmood, Borroni, Emanuele, Trovato, Alberto, Tahseen, Sabira, Cirillo, Daniela Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709449/
https://www.ncbi.nlm.nih.gov/pubmed/31262765
http://dx.doi.org/10.1128/AAC.00915-19