Downregulation of Nodal inhibits metastatic progression in retinoblastoma

Retinoblastoma is the most common intraocular malignancy in children. We previously found that the ACVR1C/SMAD2 pathway is significantly upregulated in invasive retinoblastoma samples from patients. Here we studied the role of an ACVR1C ligand, Nodal, in regulating growth and metastatic disseminatio...

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Detalles Bibliográficos
Autores principales: Asnaghi, Laura, White, David T., Yoon, Lynn, Price, Antoinette, Lee, Grace Y., Sahoo, Arpan, Mumm, Jeff S., Eberhart, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709548/
https://www.ncbi.nlm.nih.gov/pubmed/31451106
http://dx.doi.org/10.1186/s40478-019-0785-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709548/
https://www.ncbi.nlm.nih.gov/pubmed/31451106
http://dx.doi.org/10.1186/s40478-019-0785-4

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