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A ROS-responsive polymeric prodrug nanosystem with self-amplified drug release for PSMA (−) prostate cancer specific therapy

BACKGROUND: The selectively accumulate in tumor site and completely release drug within cancer cells great limit the therapeutic effect of nano-drug delivery system. Moreover, absence of appropriate biomarker is one of the major challenges for prostate specific membrane antigen negative (PSMA (−)) p...

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Detalles Bibliográficos
Autores principales: Wang, Yifan, Zhang, Yanqiu, Ru, Zhengxing, Song, Wei, Chen, Lin, Ma, Hao, Sun, Lizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709549/
https://www.ncbi.nlm.nih.gov/pubmed/31451114
http://dx.doi.org/10.1186/s12951-019-0521-z